Why Reporting - Not Just Sequencing - Defines Genomic Value
As genomic testing becomes more embedded in mainstream care, from pharmacogenomics (PGx) to oncology, health systems are making major investments in sequencing capacity, interpretation tools, and pipeline infrastructure.
But one critical piece often gets overlooked: the final report.
A clinician-ready genomic report isn’t just a data dump of detected variants. It’s a carefully structured, clinically relevant summary that empowers non-genetics-trained providers to make timely, confident decisions at the point of care. In short, if your genomic reports aren’t clinician-ready, your program isn’t ready either.
The Stakes Are High: Why Report Clarity Matters
Whether the end user is a pharmacist managing polypharmacy, an oncologist evaluating therapy options, or a PCP reviewing pharmacogenomic risk before initiating treatment, the report must do more than summarize findings. It must translate them into action.
A poorly structured or overly technical genomic report creates friction:
- Clinicians delay decisions while clarifying results
- Reports get ignored or misinterpreted
- Follow-up coordination breaks down
- The perceived value of the entire genomic program diminishes
By contrast, a clinician-ready report accelerates care, strengthens trust, and improves ROI on genomic infrastructure.
5 Elements of a Clinician-Ready Genomic Report
Based on our work with health systems deploying genomic workflows at scale, here are five essentials that separate high-utility clinical reports from everything else:
Clear Variant-to-Therapy Mapping
Every variant listed should include a brief, evidence-backed statement connecting the mutation to therapeutic relevance, or its lack thereof. If a detected variant doesn’t change the clinical picture, say so.
Why it matters: Providers need to know what’s relevant right now, not just what’s possible.
Structured, Familiar Formatting
Think problem-oriented structure: summary first, followed by variant detail, interpretation, and methodology. Use layouts that echo existing lab or imaging reports when possible.
Why it matters: The more cognitively aligned the report is with existing workflows, the faster it gets acted on.
Actionability at a Glance
Use color-coded flags or decision support cues to highlight drug-gene interactions, contraindications, or high-impact mutations.
Why it matters:
Clinicians skim. Make important findings unmissable without hiding nuance.Templated for Consistency
Reports should be consistent in structure across test types and specialties, whether they’re PGx, tumor profiling, or hereditary panels.
Why it matters:
Consistency builds trust. Variable formats increase cognitive load and introduce uncertainty.Integrated or Ready for EHR Ingestion
At minimum, reports should be exportable in formats compatible with EHR systems (PDF + structured data). Ideally, they’re ready to plug into clinical workflows via HL7/FHIR or direct API push.
Why it matters: If your genomic report lives outside the EHR, it’s already a step removed from the care decision.
How PraediGene Supports Clinician-Ready Reporting
At Bitscopic, we designed PraediGene not just to process sequencing data but to deliver reports that clinicians can use immediately. Every report is:
- Templated for readability and consistency
- Annotated with PharmWatch and SlyVIA for interpretive clarity
- Configurable to align with institutional preferences
- Delivered in formats ready for downstream integration
Whether you’re launching a PGx program or expanding tumor profiling, PraediGene helps ensure your final output isn’t just clinically valid, it’s clinically usable.
Genomic Reporting Is Clinical Communication
The best sequencing in the world means nothing if the clinician reading the report doesn’t know what to do next. That’s why reporting is not just a technical deliverable, it’s a clinical act. Let’s treat it like one.
WANT TO SEE A SAMPLE CLINICAL GENOMICS REPORT FROM PRAEDIGENE?
Our team is excited to demonstrate why PraediGene reporting is right for you.