PRAEDIGENE

The Future of Dry Lab Bioinformatics for Pharmacogenomics and Precision Oncology

Advanced Genomic Reporting and Analytics

PraediGene delivers powerful, streamlined genomic analytics and reporting to optimize lab efficiency and enhance patient care. Trusted by leading institutions, including the Department of Veterans Affairs, PraediGene seamlessly handles complex genomic workflows, drastically reducing the turnaround time from sequencing to actionable clinical insights.

Precision Oncology: Transforming Somatic Genetics Data Into Action

PraediGene’s precision oncology solutions facilitate precise treatment strategies through comprehensive genomic profiling and advanced analytical pipelines.

Key Oncology Capabilities:

Profiling and interpretation for common, large cancer panels – including Illumina’s TruSight Oncology 500 panel and Pillar’s 50+ gene oncoReveal Myeloid Panel
Support for smaller panels targeting key cancer-risk genes (e.g., BRCA1/2, JAK2, CALR, MPL, etc).
Robust, streamlined clinical reporting with intuitive visualization of oncology-related genetic data.

Core Benefits for Oncology:

Rapid identification of actionable genetic mutations to inform targeted therapy choices.
Clinical trial matching.
Integration with clinical decision support systems (CDSS) for informed, personalized oncology treatments.

Pharmacogenomics: Precision in Medication Management

PraediGene revolutionizes pharmacogenomics by precisely predicting medication responses based on individual genetic profiles, significantly reducing adverse drug reactions and enhancing therapeutic effectiveness.

Key Pharmacogenomic Capabilities:

Comprehensive pharmacogenomic pipeline utilizing advanced tools built on top of standard industry software and knowledge repositories.
Accurate identification and interpretation of genetic variants affecting drug metabolism and efficacy.
Holistic analysis incorporating full contextual genetic picture.
FHIR/HL7: Automated, actionable pharmacogenomic reports integrated directly into HER via standard interfaces.

Core Benefits for Pharmacogenomics:

Personalized medication recommendations to optimize patient safety and treatment outcomes.
Reduction in medication-related hospitalizations through precise drug efficacy predictions.
Enhanced clinical decision-making with clear, actionable insights.
Increased patient satisfaction and improved experience.

Comprehensive Genomics Knowledgebase

PraediGene features an integrated knowledge base that is continuously updated with clinical evidence, variant classifications, clinical trials and therapeutic recommendations. Our knowledge base enhances test accuracy and supports rapid clinical decision-making by providing actionable, evidence-based insights.

The knowledge base is continuously updated as results are interpreted, classified and reported helping minimize re-interpretation, decreasing costs and enabling increased testing volume.

Laboratory Developed Testing (LDT)

Bitscopic offers broad support and partnerships for Laboratory Developed Tests helping you bring new tests to market or bring genomics testing capabilities in-house.

Validation – Robust dry lab bioinformatics services and processes to help ensure your wet lab results and test performance characteristics are adequate.
Regulatory – Comprehensive dry lab compliance with guidelines (e.g. CAP, CLIA).
Commercialization – Launch and advertise your new tests and introduce new revenue streams into your laboratory.

Multi-tier Analysis Support

PraediGene empowers genomic laboratories with comprehensive bioinformatics services, streamlining primary, secondary, and tertiary analyses:

Primary – Robust management of sequencing data directly from instrumentation, ensuring accurate data quality control and rapid initial processing.
Secondary – Automated variant calling and alignment utilizing industry-leading bioinformatics pipelines to deliver precise genomic data swiftly and reliably.
Tertiary – Advanced variant interpretation, annotation, and actionable clinical reporting customized to your lab’s specific LDT protocols and clinical requirements.

Proven Scalability and Effectiveness

PraediGene has been successfully deployed in large-scale projects within the VA National Reference Labs, including the VA “SeqForce” COVID genome sequencing initiative, which has handled over 280,000 samples with high precision and reliability.

Key Features and Benefits for Genomics Laboratories

Feature	Benefits
Seamless EHR & LIS Integration	Automated data integration with systems like VistA, eliminating errors and streamlining workflows.
Comprehensive Variant Analysis	Accurate identification and interpretation of common and rare genetic variants, enabling precise clinical actions.
Automated Report Generation	Standardized, clinical-grade, user-friendly reports with detailed genetic analysis and actionable insights.
Regulatory Compliance & Data Security	Strict adherence to regulatory standards ensures the security of patient data and compliance.
Financial Management Tools	Automated invoicing, comprehensive financial analytics, and streamlined billing processes.
Dynamic Response Platform	Flexible platform capable of adapting to evolving healthcare demands without compromising analysis quality.

Empower Your Genomics Capabilities Today

Bitscopic’s multidisciplinary team of clinicians, genomic scientists, and technologists is committed to advancing your clinical genomics practice through precision medicine.

Bitscopic is a healthcare technology company delivering decision-ready data to support clinical, operational, and research excellence. Our interoperable solutions help health systems turn complex data into clear, actionable insights that improve outcomes and accelerate innovation. With a decade of experience in federal and commercial health, we’re trusted by the people making the most important decisions in healthcare.